Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | ADK | P55263 | 4/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14111447 | 0.90 | HIF1A (0.42) | HIF1ATP53STAT6ADORA3ADORA2A | |
| SCHEMBL13598738 | 0.89 | ADORA3 (0.50) | HIF1ATP53STAT6ADORA3ADORA2A | |
| SCHEMBL4423773 | 0.89 | ADORA3 (0.50) | HIF1ATP53STAT6ADORA3ADORA2A | |
| SCHEMBL13598692 | 0.89 | ADORA3 (0.50) | HIF1ATP53STAT6ADORA3ADORA2A | |
| SCHEMBL4424317 | 0.89 | ADORA3 (0.50) | HIF1ATP53STAT6ADORA3ADORA2A | |
| SCHEMBL14111464 | 0.89 | ADORA3 (0.37) | HIF1ATP53ADORA3ADORA2AADORA1 | |
| SCHEMBL14111458 | 0.89 | HIF1A (0.44) | HIF1ATP53STAT6ADORA3ADORA2A | |
| SCHEMBL14111503 | 0.89 | HIF1A (0.42) | HIF1ATP53STAT6ADORA3ADORA2A | |
| SCHEMBL14111476 | 0.88 | ADORA3 (0.39) | HIF1ATP53ADORA3ADORA2AADORA1 | |
| SCHEMBL14111456 | 0.88 | HIF1A (0.44) | HIF1ATP53STAT6ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7405204-B2 | Nucleoside compounds for treating viral infections | GENELABS TECHNOLOGIES, INC. (US) | 2008-07-29 | — | — | US | disclosed |
| US-7405204-B2 | Nucleoside compounds for treating viral infections | GENELABS TECHNOLOGIES, INC. (US) | 2008-07-29 | — | — | US | disclosed |