Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 18/20 | 0.70 |
| ▸ | PTGER4 | P35408 | 17/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14113063 | 0.94 | PTGER2 (0.79) | PTGER2PTGER4SMN1; SMN2HRH3 | |
| SCHEMBL1056318 | 0.89 | PTGER2 (0.89) | PTGER2PTGER4PTGER3 | |
| SCHEMBL1055158 | 0.82 | PTGER2 (1.00) | PTGER2PTGER4PTGER3 | |
| SCHEMBL13844697 | 0.76 | PTGER2 (0.56) | PTGER2PTGER4SMN1; SMN2HRH3 | |
| SCHEMBL14113065 | 0.75 | PTGER2 (0.54) | PTGER2PTGER4SMN1; SMN2HRH3 | |
| SCHEMBL1058786 | 0.74 | PTGER2 (0.94) | PTGER2PTGER4PTGER3 | |
| SCHEMBL4597634 | 0.74 | PTGER2 (1.00) | PTGER2PTGER4PTGER3 | |
| SCHEMBL14219542 | 0.74 | PTGER2 (0.74) | PTGER2PTGER4PTGER3 | |
| SCHEMBL14220080 | 0.74 | PTGER2 (0.74) | PTGER2PTGER4PTGER3 | |
| SCHEMBL4597638 | 0.74 | PTGER2 (1.00) | PTGER2PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410991-B2 | Pyrazolidinone compounds as ligands of the prostaglandin EP2 and/or EP4 receptors | LABORATOIRES SERONO S.A. (CH) | 2008-08-12 | — | — | US | disclosed |