Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 13/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14394702 | 0.88 | MEN1 (0.62) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL5496575 | 0.79 | RXFP1 (0.74) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL5496719 | 0.79 | RXFP1 (0.60) | MAPTRXFP1P2RX1SMN1; SMN2PTGS1 | |
| SCHEMBL330133 | 0.79 | P2RX1 (0.73) | MEN1KMT2AMAPTRXFP1P2RX1 | |
| SCHEMBL14112994 | 0.77 | CYP1A2 (0.50) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL13315734 | 0.76 | RXFP1 (0.64) | RXFP1LMNAP2RX1SMN1; SMN2HTT | |
| SCHEMBL21416908 | 0.74 | RXFP1 (0.52) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL22025431 | 0.73 | RXFP1 (0.67) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL22025011 | 0.73 | RXFP1 (0.67) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL5496729 | 0.73 | MEN1 (0.72) | CYP1A2CYP3A4CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080167347-A1 | Antidiabetic, antiproliferative, anticancer agents; benzanilide derivatives | SHIONGI & CO., LTD. (JP) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167347-A1 | Antidiabetic, antiproliferative, anticancer agents; benzanilide derivatives | CCNY, HDGF, GLI1 | CYP1A2 4202/4885CYP3A4 3548/4885CYP2C19 3287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.