Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJA1 | P17302 | 1/20 | 0.38 |
| ▸ | GJB2 | P29033 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.38 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.38 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.38 |
| ▸ | IDUA | P35475 | 1/20 | 0.36 |
| ▸ | LRAT | O95237 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | HOGA1 | Q86XE5 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14088638 | 1.00 | GJA1 (0.38) | GJA1GJB2MEN1CYP2C9TSHR | |
| SCHEMBL12361504 | 1.00 | GJA1 (0.38) | GJA1GJB2MEN1CYP2C9TSHR | |
| SCHEMBL1133598 | 1.00 | GJA1 (0.38) | GJA1GJB2MEN1CYP2C9TSHR | |
| SCHEMBL14265111 | 1.00 | GJA1 (0.38) | GJA1GJB2MEN1CYP2C9TSHR | |
| SCHEMBL13852179 | 1.00 | GJA1 (0.38) | GJA1GJB2MEN1CYP2C9TSHR | |
| SCHEMBL23517631 | 1.00 | GJA1 (0.38) | GJA1GJB2MEN1CYP2C9TSHR | |
| SCHEMBL14601102 | 1.00 | GJA1 (0.38) | GJA1GJB2MEN1CYP2C9TSHR | |
| SCHEMBL10025639 | 1.00 | GJA1 (0.38) | GJA1GJB2MEN1CYP2C9TSHR | |
| SCHEMBL21001789 | 1.00 | GJA1 (0.38) | GJA1GJB2MEN1CYP2C9TSHR | |
| SCHEMBL13857459 | 1.00 | GJA1 (0.38) | GJA1GJB2MEN1CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7416858-B2 | Pharmaceutical compositions of glycoconjugates | NEOSE TECHNOLOGIES, INC. (US) | 2008-08-26 | — | — | US | disclosed |