Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 5/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.36 |
| ▸ | ALB | P02768 | 2/20 | 0.34 |
| ▸ | PADI1 | Q9ULC6 | 2/20 | 0.33 |
| ▸ | PADI3 | Q9ULW8 | 2/20 | 0.33 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.33 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.33 |
| ▸ | RRM1 | P23921 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GART | P22102 | 2/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4986857 | 0.85 | C3AR1 (0.45) | C3AR1FOLH1ALBEPHX2CA2 | |
| SCHEMBL14090877 | 0.76 | NPSR1 (0.44) | KDM4E | |
| SCHEMBL14147095 | 0.74 | C3AR1 (0.42) | C3AR1FOLH1EPHX2 | |
| SCHEMBL4997732 | 0.71 | C3AR1 (0.45) | C3AR1PADI1PADI3PADI4PADI2 | |
| SCHEMBL4991048 | 0.71 | PLG (0.39) | — | |
| SCHEMBL4433955 | 0.69 | C3AR1 (0.43) | C3AR1FOLH1EPHX2 | |
| SCHEMBL2615859 | 0.68 | FOLH1 (0.49) | FOLH1ALBPADI1PADI3PADI4 | |
| SCHEMBL4986587 | 0.68 | BRD4 (0.52) | C3AR1FOLH1ALBKDM4E | |
| SCHEMBL4430961 | 0.68 | C3AR1 (0.37) | C3AR1FOLH1KDM4E | |
| SCHEMBL14366288 | 0.67 | FOLH1 (0.46) | C3AR1FOLH1ALBPADI1PADI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | ENCYSIVE PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | C3AR1, C5, C5AR1 | C3AR1 1/4885FOLH1 2725/4885ALB 1064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.