Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 11/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4986857 | 0.88 | C3AR1 (0.45) | C3AR1FOLH1TPSAB1EPHX2 | |
| SCHEMBL4997732 | 0.76 | C3AR1 (0.45) | C3AR1 | |
| SCHEMBL14115154 | 0.74 | C3AR1 (0.37) | C3AR1FOLH1EPHX2 | |
| SCHEMBL4566055 | 0.73 | C3AR1 (0.45) | C3AR1 | |
| SCHEMBL4991622 | 0.73 | C3AR1 (0.45) | C3AR1 | |
| SCHEMBL4986587 | 0.71 | BRD4 (0.52) | C3AR1FOLH1 | |
| SCHEMBL4990654 | 0.70 | C3AR1 (0.45) | C3AR1FOLH1 | |
| SCHEMBL188589 | 0.70 | C3AR1 (0.52) | C3AR1FOLH1 | |
| SCHEMBL7925397 | 0.70 | C3AR1 (0.52) | C3AR1FOLH1 | |
| SCHEMBL188590 | 0.70 | C3AR1 (0.52) | C3AR1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008079371-A1 | MODULATORS OF C3A RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-07-03 | — | — | WO | disclosed |