Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 10/20 | 0.55 |
| ▸ | MC1R | Q01726 | 4/20 | 0.55 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.51 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.51 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.51 |
| ▸ | CCKBR | P32239 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSH | P09668 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306027 | 0.92 | IL23R (0.56) | MC4RMC1RIL23RKISS1R | |
| SCHEMBL1449964 | 0.92 | IL23R (0.56) | MC4RMC1RIL23RKISS1R | |
| SCHEMBL28714609 | 0.91 | IL23R (0.56) | MC4RMC1RIL23RKISS1RCCKBR | |
| SCHEMBL30464987 | 0.90 | IL23R (0.57) | MC4RIL23RKISS1RCCKBR | |
| SCHEMBL22485392 | 0.90 | MC4R (0.54) | MC4RNPBWR1KISS1RCCKBR | |
| SCHEMBL18891483 | 0.89 | MC4R (0.62) | MC4RIL23RKISS1RCCKBRCTSL | |
| SCHEMBL18891548 | 0.89 | MC4R (0.62) | MC4RIL23RKISS1RCCKBRCTSL | |
| SCHEMBL22339063 | 0.89 | MC4R (0.53) | MC4RNPBWR1KISS1RCCKBRCTSL | |
| SCHEMBL1371627 | 0.89 | C5AR1 (0.56) | MC4RNPBWR1IL23R | |
| SCHEMBL1371631 | 0.89 | C5AR1 (0.56) | MC4RNPBWR1IL23R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080177036-A1 | Selective Linear Peptides with Melanocortin-4 Receptor (MC4-R) Agonist Activity | CHEN LI | 2008-07-24 | — | — | US | disclosed |
| US-20080177036-A1 | Selective Linear Peptides with Melanocortin-4 Receptor (MC4-R) Agonist Activity | CHEN LI | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080177036-A1 | Selective Linear Peptides with Melanocortin-4 Receptor (MC4-R) Agonist Activity | MC4R, MC3R, MC1R | MC4R 1/4885MC1R 3/4885NPBWR1 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.