SCHEMBL22485392

SCHEMBL22485392

CCCCCCCCNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CCCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 5/20 0.54
▸ CCKBR P32239 3/20 0.53
▸ PRKACB P22694 1/20 0.53
▸ NPBWR1 P48145 1/20 0.52
▸ KISS1R Q969F8 2/20 0.51
▸ NPFFR1 Q9GZQ6 1/20 0.51
▸ C5AR1 P21730 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22339063 0.93 MC4R (0.53) MC4RCCKBRPRKACBNPBWR1KISS1R
SCHEMBL14811912 0.92 MC4R (0.57) MC4RCCKBRNPBWR1KISS1R
SCHEMBL22485206 0.92 MC4R (0.50) MC4RCCKBRPRKACBNPBWR1KISS1R
SCHEMBL14117706 0.90 MC4R (0.55) MC4RCCKBRNPBWR1KISS1R
SCHEMBL22485368 0.90 MC4R (0.50) MC4RCCKBRPRKACBNPBWR1KISS1R
SCHEMBL22339064 0.89 MC4R (0.55) MC4RCCKBRNPBWR1KISS1R
SCHEMBL22339065 0.88 CCKBR (0.63) MC4RCCKBRKISS1R
SCHEMBL15691474 0.87 NPBWR1 (0.52) MC4RCCKBRPRKACBNPBWR1KISS1R
SCHEMBL5501891 0.86 KISS1R (0.55) MC4RNPBWR1KISS1R
SCHEMBL18891483 0.86 MC4R (0.62) MC4RCCKBRKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200308222-A1 ANTIMICROBIAL TETRAPEPTIDES DSM IP ASSETS B.V. (NL) 2020-10-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200308222-A1 ANTIMICROBIAL TETRAPEPTIDES VIP, CLPP, SGTA MC4R 1528/4885CCKBR 2568/4885PRKACB 1908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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