Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 4/20 | 0.43 |
| ▸ | GALK1 | P51570 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | PLEC | Q15149 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PYGM | P11217 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798408 | 0.84 | ALDH1A1 (0.43) | POLBTDP1LMNAMCL1ALDH1A1 | |
| SCHEMBL28133405 | 0.81 | ALDH1A1 (0.55) | POLBHPSETDP1LMNAPYGL | |
| SCHEMBL522949 | 0.80 | POLB (0.77) | POLBHPSETDP1LMNAPYGL | |
| SCHEMBL30287662 | 0.80 | POLB (0.77) | POLBHPSETDP1LMNAPYGL | |
| SCHEMBL28576596 | 0.78 | POLB (0.75) | POLBHPSETDP1LMNAPYGL | |
| SCHEMBL29406842 | 0.78 | POLB (0.73) | POLBHPSETDP1LMNAPYGL | |
| SCHEMBL30553345 | 0.78 | POLB (0.73) | POLBHPSETDP1LMNAPYGL | |
| SCHEMBL30901880 | 0.78 | POLB (0.73) | POLBHPSETDP1LMNAPYGL | |
| SCHEMBL145176 | 0.78 | POLB (0.73) | POLBHPSETDP1LMNAPYGL | |
| SCHEMBL262311 | 0.78 | POLB (0.73) | POLBHPSETDP1LMNAPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8668992-B2 | Fluorinated polyimides with fluorene cardo structure as optical materials that have low absolute thermo-optic coefficients | BREWER SCIENCE INC. (US) | 2014-03-11 | — | — | US | disclosed |
| US-20120308835-A1 | FLUORINATED POLYIMIDES WITH FLUORENE CARDO STRUCTURE AS OPTICAL MATERIALS THAT HAVE LOW ABSOLUTE THERMO-OPTIC COEFFICIENTS | BREWER SCIENCE INC. (US) | 2012-12-06 | — | — | US | disclosed |