Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14123908 | 0.88 | TDP1 (0.54) | TDP1CYP3A4 | |
| SCHEMBL18715750 | 0.87 | CYP3A4 (0.65) | CYP3A4 | |
| SCHEMBL21946533 | 0.87 | CYP3A4 (0.65) | CYP3A4 | |
| SCHEMBL14123814 | 0.86 | CYP3A4 (0.56) | TDP1CYP3A4 | |
| SCHEMBL11919313 | 0.84 | RAB9A (0.48) | TDP1CYP3A4 | |
| SCHEMBL2736231 | 0.83 | CYP3A4 (0.66) | CYP3A4 | |
| SCHEMBL10067531 | 0.83 | CYP3A4 (0.66) | CYP3A4 | |
| SCHEMBL18715783 | 0.83 | CYP3A4 (0.66) | CYP3A4 | |
| SCHEMBL2736188 | 0.83 | CYP3A4 (0.66) | CYP3A4 | |
| SCHEMBL18715718 | 0.82 | CYP3A4 (0.56) | TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008103949-A1 | MODULATORS OF PHARMACOKINETIC PROPERTIES OF THERAPEUTICS | GILEAD SCIENCES, INC. (US) | 2008-08-28 | — | — | WO | disclosed |