Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 6/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2602494 | 1.00 | LMNA (0.43) | LMNAPOLBAPEX1HTTTDP1 | |
| SCHEMBL2602459 | 0.99 | LMNA (0.43) | LMNAPOLBAPEX1HTTTDP1 | |
| SCHEMBL10160381 | 0.99 | LMNA (0.43) | LMNAPOLBAPEX1HTTTDP1 | |
| SCHEMBL22939199 | 0.98 | LMNA (0.42) | LMNAPOLBAPEX1HTTTDP1 | |
| SCHEMBL2602492 | 0.97 | LMNA (0.43) | LMNAPOLBAPEX1HTTTDP1 | |
| SCHEMBL14981829 | 0.97 | LMNA (0.43) | LMNAPOLBAPEX1HTTTDP1 | |
| SCHEMBL10160377 | 0.97 | LMNA (0.43) | LMNAPOLBAPEX1HTTTDP1 | |
| SCHEMBL10160384 | 0.97 | LMNA (0.43) | LMNAPOLBAPEX1HTTTDP1 | |
| SCHEMBL2602456 | 0.96 | LMNA (0.47) | LMNAPOLBAPEX1HTTTDP1 | |
| SCHEMBL12925369 | 0.96 | LMNA (0.47) | LMNAPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735032-B2 | Electrophotographic photosensitive member, method of producing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2014-05-27 | — | — | US | disclosed |
| US-20120301178-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2012-11-29 | — | — | US | disclosed |