SCHEMBL14124804

SCHEMBL14124804

O=C(O)c1ccc(C(=O)c2ccc3sc4ccccc4c3c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.60
SRD5A2 P31213 8/20 0.53
PTPN7 P35236 1/20 0.47
DUSP3 P51452 1/20 0.47
PTPN12 Q05209 1/20 0.47
PTPN22 Q9Y2R2 1/20 0.47
GPR3 P46089 1/20 0.45
ATM Q13315 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP2C8 P10632 1/20 0.44
CYP2C9 P11712 1/20 0.44
MAPT P10636 1/20 0.43
MAOB P27338 1/20 0.43
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
MCL1 Q07820 1/20 0.42
GABRA1 P14867 1/20 0.42
GABRA5 P31644 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1576859 0.93 CYP1A2 (0.63) CYP1A2SRD5A2PTPN7DUSP3PTPN12
SCHEMBL30839928 0.90 CYP1A2 (0.67) CYP1A2PTPN7DUSP3PTPN12PTPN22
SCHEMBL3111619 0.90 CYP1A2 (0.67) CYP1A2PTPN7DUSP3PTPN12PTPN22
SCHEMBL16456435 0.86 CYP1A2 (0.55) CYP1A2PTPN7DUSP3PTPN12PTPN22
SCHEMBL31379443 0.86 CYP1A2 (0.55) CYP1A2PTPN7DUSP3PTPN12PTPN22
SCHEMBL1576689 0.86 MAOB (0.60) CYP1A2SRD5A2PTPN7DUSP3PTPN12
SCHEMBL17931031 0.86 CYP1A2 (0.55) CYP1A2PTPN7DUSP3PTPN12PTPN22
SCHEMBL16447180 0.85 CYP1A2 (0.55) CYP1A2PTPN7DUSP3PTPN12PTPN22
SCHEMBL2330767 0.84 CDC25B (0.58) CYP1A2PTPN7DUSP3PTPN12PTPN22
Dibenzothiophene SCHEMBL8068874 0.82 TSHR (0.61) CYP1A2SRD5A2PTPN7DUSP3PTPN12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7396488-B2 Light emitting device and fluorescent material MITSUBISHI CHEMICAL CORPORATION (JP) 2008-07-08 US disclosed
US-7396488-B2 Light emitting device and fluorescent material MITSUBISHI CHEMICAL CORPORATION (JP) 2008-07-08 US disclosed
US-7282160-B2 Light emitting device and fluorescent material MITSUBISHI CHEMICAL CORPORATION (JP) 2007-10-16 US disclosed
US-7282160-B2 Light emitting device and fluorescent material MITSUBISHI CHEMICAL CORPORATION (JP) 2007-10-16 US disclosed
US-20070085057-A1 LIGHT EMITTING DEVICE AND FLUORESCENT MATERIAL MITSUBISHI CHEMICAL CORPORATION (JP) 2007-04-19 US disclosed
US-20070085057-A1 LIGHT EMITTING DEVICE AND FLUORESCENT MATERIAL MITSUBISHI CHEMICAL CORPORATION (JP) 2007-04-19 US disclosed