SCHEMBL2330767

SCHEMBL2330767

O=C(O)c1ccccc1C(=O)c1ccc2sc3ccccc3c2c1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 5/20 0.58
CDC25A P30304 1/20 0.58
HSD17B10 Q99714 1/20 0.58
CYP1A2 P05177 1/20 0.57
PRNP P04156 1/20 0.55
RXFP1 Q9HBX9 1/20 0.55
ALDH1A1 P00352 2/20 0.53
AKR1C3 P42330 3/20 0.51
ATM Q13315 1/20 0.50
LMNA P02545 1/20 0.49
POLB P06746 2/20 0.49
NR4A1 P22736 1/20 0.49
KDM4E B2RXH2 1/20 0.45
PTPN7 P35236 1/20 0.45
DUSP3 P51452 1/20 0.45
PTPN12 Q05209 1/20 0.45
PTPN22 Q9Y2R2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14124804 0.84 CYP1A2 (0.60) CYP1A2ATMPTPN7DUSP3PTPN12
SCHEMBL1576859 0.84 CYP1A2 (0.63) CYP1A2ALDH1A1ATMPTPN7DUSP3
SCHEMBL30839928 0.84 CYP1A2 (0.67) CYP1A2ALDH1A1LMNAKDM4EPTPN7
SCHEMBL3111619 0.84 CYP1A2 (0.67) CYP1A2ALDH1A1LMNAKDM4EPTPN7
SCHEMBL26232808 0.84 CYP1A2 (0.52) CDC25BCDC25AHSD17B10CYP1A2PRNP
SCHEMBL1576690 0.84 CYP1A2 (0.52) CYP1A2PRNPRXFP1ALDH1A1POLB
SCHEMBL14378409 0.82 CDC25B (0.48) CDC25BCDC25AHSD17B10CYP1A2PRNP
SCHEMBL14124816 0.81 AKR1C3 (0.56) CDC25BCDC25AHSD17B10CYP1A2PRNP
SCHEMBL12479316 0.80 CDC25B (0.70) CDC25BCDC25AHSD17B10PRNPALDH1A1
SCHEMBL14124815 0.80 CYP1A2 (0.49) CDC25BCDC25AHSD17B10CYP1A2PRNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8821762-B2 Anthra[2,3-b]benzo[d]thiophene derivatives and their use as organic semiconductors MERCK PATENT GMBH (DE) 2014-09-02 US claimed
US-20110248220-A1 Anthra[2,3-b]benzo[d]thiophene Derivatives and their Use as Organic Semiconductors MERCK PATENT GESELLSCHAFT (GB) 2011-10-13 US claimed
EP-2358696-A1 ANTHRAÝ2,3-B¨BENZOÝD¨THIOPHENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS Merck Patent GmbH (DE) 2011-08-24 EP claimed
WO-2010069457-A1 ANTHRA[2,3-B]BENZO[D]THIOPHENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2010-06-24 WO claimed
US-8821762-B2 Anthra[2,3-b]benzo[d]thiophene derivatives and their use as organic semiconductors MERCK PATENT GMBH (DE) 2014-09-02 US disclosed
US-8821762-B2 Anthra[2,3-b]benzo[d]thiophene derivatives and their use as organic semiconductors MERCK PATENT GMBH (DE) 2014-09-02 US disclosed
US-8821762-B2 Anthra[2,3-b]benzo[d]thiophene derivatives and their use as organic semiconductors MERCK PATENT GMBH (DE) 2014-09-02 US disclosed
US-20140027757-A1 NOVEL SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2014-01-30 US disclosed
US-20140027757-A1 NOVEL SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2014-01-30 US disclosed
US-20110248220-A1 Anthra[2,3-b]benzo[d]thiophene Derivatives and their Use as Organic Semiconductors MERCK PATENT GESELLSCHAFT (GB) 2011-10-13 US disclosed
US-20110248220-A1 Anthra[2,3-b]benzo[d]thiophene Derivatives and their Use as Organic Semiconductors MERCK PATENT GESELLSCHAFT (GB) 2011-10-13 US disclosed
US-20110248220-A1 Anthra[2,3-b]benzo[d]thiophene Derivatives and their Use as Organic Semiconductors MERCK PATENT GESELLSCHAFT (GB) 2011-10-13 US disclosed
WO-2010069457-A1 ANTHRA[2,3-B]BENZO[D]THIOPHENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2010-06-24 WO disclosed
WO-2010069457-A1 ANTHRA[2,3-B]BENZO[D]THIOPHENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2010-06-24 WO disclosed
US-7396488-B2 Light emitting device and fluorescent material MITSUBISHI CHEMICAL CORPORATION (JP) 2008-07-08 US disclosed
US-7396488-B2 Light emitting device and fluorescent material MITSUBISHI CHEMICAL CORPORATION (JP) 2008-07-08 US disclosed
US-7282160-B2 Light emitting device and fluorescent material MITSUBISHI CHEMICAL CORPORATION (JP) 2007-10-16 US disclosed
US-7282160-B2 Light emitting device and fluorescent material MITSUBISHI CHEMICAL CORPORATION (JP) 2007-10-16 US disclosed
US-20070085057-A1 LIGHT EMITTING DEVICE AND FLUORESCENT MATERIAL MITSUBISHI CHEMICAL CORPORATION (JP) 2007-04-19 US disclosed
US-20070085057-A1 LIGHT EMITTING DEVICE AND FLUORESCENT MATERIAL MITSUBISHI CHEMICAL CORPORATION (JP) 2007-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110248220-A1 Anthra[2,3-b]benzo[d]thiophene Derivatives and their Use as Organic Semiconductors ANTXR2, TST, ANXA2 CDC25B 110/4885CDC25A 373/4885HSD17B10 3404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.