Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 18/20 | 0.64 |
| ▸ | MAOB | P27338 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14125330 | 0.84 | PYCR1 (0.66) | PYCR1MAOBLMNAMAOAUSP2 | |
| SCHEMBL11896612 | 0.80 | PYCR1 (0.72) | PYCR1MAOBLMNAMAOAUSP2 | |
| SCHEMBL10033809 | 0.78 | PYCR1 (1.00) | PYCR1MAOBLMNAMAOAUSP2 | |
| SCHEMBL8244727 | 0.78 | PYCR1 (0.72) | PYCR1MAOBLMNAMAOAUSP2 | |
| SCHEMBL10033791 | 0.78 | PYCR1 (0.57) | PYCR1MAOBLMNAMAOAUSP2 | |
| SCHEMBL5680713 | 0.77 | PYCR1 (0.70) | PYCR1MAOBLMNAMAOAUSP2 | |
| SCHEMBL711329 | 0.77 | PYCR1 (0.70) | PYCR1MAOBLMNAMAOAUSP2 | |
| Pargyline SCHEMBL18036659 | 0.76 | PYCR1 (1.00) | PYCR1MAOBLMNAMAOAUSP2 | |
| Pargyline SCHEMBL2045 | 0.76 | PYCR1 (1.00) | PYCR1MAOBLMNAMAOAUSP2 | |
| Pargyline SCHEMBL7363311 | 0.74 | PYCR1 (0.96) | PYCR1MAOBLMNAMAOAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008092091-A2 | MAO INHIBITING N-BENZYL-N-PROPARGYL-AMINES USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY (US) | 2008-07-31 | — | — | WO | disclosed |