SCHEMBL141269

SCHEMBL141269

NCCC(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10724979 0.97
SCHEMBL4289094 0.80
Hydrochloric Acid SCHEMBL9128032 0.78
SCHEMBL17635398 0.78
SCHEMBL43375 0.76
SCHEMBL4631712 0.76
SCHEMBL4562529 0.76 ALDH1A1 (0.59)
SCHEMBL6516805 0.76 ALDH1A1 (0.59)
SCHEMBL2205371 0.76 ALDH1A1 (0.59)
Hydrochloric Acid SCHEMBL9126393 0.74 ALDH1A1 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199745-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2024-06-20 US disclosed
CN-117025574-A Dipeptidase, dipeptidase mutant, encoding gene and application thereof 华东理工大学 2023-11-10 CN disclosed
US-20230135723-A1 ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2023-05-04 US disclosed
CN-114384756-A Resin composition, toner for developing electrostatic image, image forming method, photosensitive adhesive, and photoswitch material 柯尼卡美能达株式会社 2022-04-22 CN disclosed
US-20220107576-A1 RESIN COMPOSITION, TONER FOR DEVELOPING ELECTROSTATIC CHARGE IMAGE, IMAGE FORMING METHOD, PHOTOSENSITIVE ADHESIVE, AND OPTICAL SWITCHING MATERIAL Konica Minolta, Inc. (JP) 2022-04-07 US disclosed
US-10478512-B2 Charge-balanced imaging agents BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) 2019-11-19 US disclosed
US-10201621-B2 Charge-balanced imaging agents BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) 2019-02-12 US disclosed
US-10030036-B2 Method and dyes for detecting and destroying cancer cells LAHJAVIDA, LLC (US) 2018-07-24 US disclosed
US-20180177896-A1 CHARGE-BALANCED IMAGING AGENTS BETH ISRAEL DEACONESS MEDICAL CT INC (US) 2018-06-28 US disclosed
EP-2393420-B1 CHARGE-BALANCED IMAGING AGENTS BETH ISRAEL DEACONESS MEDICAL CT INC (US) 2018-05-30 EP disclosed
CN-101312941-A Polynucleotide labeling reagent HOFFMANN LA ROCHE (CH) 2008-11-26 CN disclosed
EP-1658269-B1 FUSED COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR ABBOTT LAB (US) 2008-10-22 EP disclosed
EP-1954671-A1 POLYNUCLEOTIDE LABELLING REAGENT Roche Diagnostics GmbH (DE) 2008-08-13 EP disclosed
US-7375217-B2 Analogs of benzoquinone-containing ansamycins and methods of use thereof INFINITY PHARMACEUTICALS, INC. (US) 2008-05-20 US disclosed
US-7361647-B2 Analogs of benzoquinone-containing ansamycins and methods of use thereof INFINITY PHARMACEUTICALS, INC. (US) 2008-04-22 US disclosed
CN-101117334-A Novel method for synthesizing L-carnosine ZHEJIANG MEDICINE CO LTD (CN) 2008-02-06 CN disclosed
US-7282493-B2 Analogs of benzoquinone-containing ansamycins and methods of use thereof INFINITY PHARMACEUTICALS, INC. (US) 2007-10-16 US disclosed
US-7282493-B2 Analogs of benzoquinone-containing ansamycins and methods of use thereof INFINITY PHARMACEUTICALS, INC. (US) 2007-10-16 US disclosed
WO-2007059912-A1 POLYNUCLEOTIDE LABELLING REAGENT ROCHE DIAGNOSTICS GMBH (DE) 2007-05-31 WO disclosed
US-4835312-A Production process of N-substituted amide compounds MITSUI CHEMICALS, INCORPORATED (JP) 1989-05-30 US disclosed