Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 3/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | RARB | P10826 | 4/20 | 0.35 |
| ▸ | RARA | P10276 | 3/20 | 0.35 |
| ▸ | RARG | P13631 | 3/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | ACLY | P53396 | 4/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.32 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.32 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2709041 | 1.00 | RXRB (0.42) | RXRBRXRARARBRARARARG | |
| SCHEMBL14855951 | 1.00 | RXRB (0.42) | RXRBRXRARARBRARARARG | |
| SCHEMBL14721790 | 0.95 | RXRB (0.41) | RXRBRXRARARBRARARARG | |
| SCHEMBL1805279 | 0.91 | RXRB (0.44) | RXRBRXRARARBRARARARG | |
| SCHEMBL14241703 | 0.89 | CHRNA1 (0.31) | RXRBRXRA | |
| SCHEMBL2708001 | 0.89 | PDK2 (0.42) | RORCACLYPDK2KCNJ6KCNJ5 | |
| SCHEMBL319708 | 0.87 | RXRB (0.56) | RXRBRXRARARBRARARARG | |
| SCHEMBL14127300 | 0.87 | PDK2 (0.31) | PDK2 | |
| SCHEMBL14127298 | 0.87 | PDK2 (0.31) | PDK2 | |
| SCHEMBL318252 | 0.86 | RXRB (0.44) | RXRBRXRARARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10869477-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2020-12-22 | — | — | US | disclosed |
| US-10869477-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2020-12-22 | — | — | US | disclosed |
| US-20180153170-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-07 | — | — | US | disclosed |
| US-20180153170-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-07 | — | — | US | disclosed |
| US-9913471-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-13 | — | — | US | disclosed |
| US-9913471-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-13 | — | — | US | disclosed |
| EP-2714666-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-02-07 | — | — | EP | disclosed |
| EP-2714666-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-02-07 | — | — | EP | disclosed |
| US-20170071207-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-16 | — | — | US | disclosed |
| US-20170071207-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-16 | — | — | US | disclosed |
| US-20140107056-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-04-17 | — | — | US | disclosed |
| US-20140107056-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-04-17 | — | — | US | disclosed |
| US-20140107056-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-04-17 | — | — | US | disclosed |
| US-20130237583-A1 | PROCESS FOR THE PREPARATION OF DIHYDROPYRROLE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-12 | — | — | US | disclosed |
| US-20130237583-A1 | PROCESS FOR THE PREPARATION OF DIHYDROPYRROLE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-12 | — | — | US | disclosed |
| US-20130237583-A1 | PROCESS FOR THE PREPARATION OF DIHYDROPYRROLE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-12 | — | — | US | disclosed |
| EP-2580211-A1 | PROCESS FOR THE PREPARATION OF DIHYDROPYRROLE DERIVATIVES | Syngenta Participations AG (CH) | 2013-04-17 | — | — | EP | disclosed |
| WO-2012163959-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-12-06 | — | — | WO | disclosed |
| WO-2011154555-A1 | PROCESS FOR THE PREPARATION OF DIHYDROPYRROLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-15 | — | — | WO | disclosed |
| WO-2011154555-A1 | PROCESS FOR THE PREPARATION OF DIHYDROPYRROLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180153170-A1 | INSECTICIDAL COMPOUNDS | CBR3, C1R, C1S | RXRB 2077/4885RXRA 2721/4885RARB 3662/4885 |
| US-20170071207-A1 | INSECTICIDAL COMPOUNDS | CBR3, C1R, C1S | RXRB 2259/4885RXRA 2695/4885RARB 3832/4885 |
| US-10869477-B2 | Insecticidal compounds | CBR3, C1R, C1S | RXRB 2077/4885RXRA 2721/4885RARB 3662/4885 |
| US-20140107056-A1 | INSECTICIDAL COMPOUNDS | CBR3, C1R, C1S | RXRB 2355/4885RXRA 2751/4885RARB 3918/4885 |
| US-20130237583-A1 | PROCESS FOR THE PREPARATION OF DIHYDROPYRROLE DERIVATIVES | CYP1A1, CYP1B1, CYP1A2 | RXRB 3622/4885RXRA 3358/4885RARB 2844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.