SCHEMBL318252

SCHEMBL318252

Cc1cc(C2=NCC(c3cc(C(F)(F)F)nc(C(F)(F)F)c3)(C(F)(F)F)C2)ccc1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RXRB P28702 2/20 0.44
RXRA P19793 1/20 0.44
RARB P10826 5/20 0.34
RARA P10276 4/20 0.34
RARG P13631 4/20 0.34
ACLY P53396 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL319708 0.88 RXRB (0.56) RXRBRXRARARBRARARARG
SCHEMBL14855951 0.86 RXRB (0.42) RXRBRXRARARBRARARARG
SCHEMBL2709041 0.86 RXRB (0.42) RXRBRXRARARBRARARARG
SCHEMBL14127331 0.86 RXRB (0.42) RXRBRXRARARBRARARARG
SCHEMBL1805279 0.85 RXRB (0.44) RXRBRXRARARBRARARARG
SCHEMBL14721790 0.81 RXRB (0.41) RXRBRXRARARBRARARARG
SCHEMBL854624 0.80 PTGS2 (0.31)
SCHEMBL318455 0.80 CACNA1H (0.37)
SCHEMBL13015189 0.78 RXRB (0.42) RXRBRXRA
SCHEMBL854560 0.76 SYK (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012004326-A1 PESTICIDAL PYRROLINE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2012-01-12 WO disclosed