SCHEMBL14128917

SCHEMBL14128917

O=C(OCBr)C1(CCCBr)CCCCC1

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.46
CYP4A11 Q02928 1/20 0.46
CYP2C19 P33261 1/20 0.35
TBXAS1 P24557 2/20 0.31
POLB P06746 1/20 0.31
PKM P14618 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
CETP P11597 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1660144 0.84 CYP4F2 (0.42) CYP4F2CYP4A11POLBPKMLMNA
SCHEMBL11296469 0.83 CYP4F2 (0.50) CYP4F2CYP4A11POLBPKMLMNA
SCHEMBL6628282 0.83 CYP4F2 (0.67) CYP4F2CYP4A11CYP2C19MAPTCETP
SCHEMBL14128918 0.80 CYP2C19 (0.52) CYP4F2CYP4A11CYP2C19TBXAS1LMNA
SCHEMBL1106769 0.79 CYP4F2 (0.45) CYP4F2CYP4A11POLBPKMLMNA
SCHEMBL187121 0.79 CYP4F2 (0.45) CYP4F2CYP4A11CYP2C19LMNACETP
SCHEMBL14129083 0.78 CYP4F2 (0.40) CYP4F2CYP4A11CYP2C19TBXAS1CETP
SCHEMBL6582129 0.78 CYP4F2 (0.70) CYP4F2CYP4A11TBXAS1MAPTCETP
SCHEMBL27519754 0.78 CYP2C19 (0.48) CYP4F2CYP4A11CYP2C19TBXAS1
SCHEMBL186860 0.77 CYP4F2 (0.48) CYP4F2CYP4A11CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9255223-B2 Polymerizable compounds and liquid crystal media MERCK PATENT GMBH (DE) 2016-02-09 US disclosed
US-20120298916-A1 POLYMERIZABLE COMPOUNDS AND LIQUID CRYSTAL MEDIA MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120298916-A1 POLYMERIZABLE COMPOUNDS AND LIQUID CRYSTAL MEDIA RCC1, CCNB2, CCNB1 CYP4F2 1516/4885CYP4A11 1016/4885CYP2C19 1979/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.