Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 6/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.42 |
| ▸ | MAP4K3 | Q8IVH8 | 3/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17480649 | 0.88 | CDK2 (0.39) | TLR9TLR8TLR7CCNE1CDK2 | |
| SCHEMBL23137881 | 0.84 | CCNE1 (0.37) | MAP4K3KMT2ACHRM4RAB9ACCNE1 | |
| SCHEMBL23136937 | 0.84 | CCNE1 (0.37) | TLR9TLR8TLR7MAP4K3CCNE1 | |
| SCHEMBL21872038 | 0.83 | CCNE1 (0.36) | MAP4K3KMT2ACHRM4RAB9ACCNE1 | |
| SCHEMBL23137885 | 0.83 | CCNE1 (0.36) | MAP4K3KMT2ACHRM4RAB9ACCNE1 | |
| SCHEMBL21872198 | 0.83 | CCNE1 (0.36) | MAP4K3KMT2ACHRM4RAB9ACCNE1 | |
| SCHEMBL9906379 | 0.79 | MLYCD (0.36) | TLR9TLR8TLR7CCNE1CDK2 | |
| SCHEMBL9906382 | 0.78 | TLR9 (0.36) | TLR9TLR8TLR7HRH3CCNE1 | |
| SCHEMBL14314252 | 0.77 | MEN1 (0.42) | TLR9TLR8TLR7MAP4K3CHRNB2 | |
| SCHEMBL9906381 | 0.75 | CCNE1 (0.35) | CCNE1CDK2CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080182837-A1 | NEW CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182837-A1 | NEW CHEMICAL COMPOUNDS | CCNA1, CCNT1, MKI67 | TLR9 4403/4885TLR8 4767/4885TLR7 3658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.