⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10413411 | 0.80 | — | — | |
| SCHEMBL673248 | 0.79 | — | — | |
| SCHEMBL13478466 | 0.79 | — | — | |
| SCHEMBL673247 | 0.79 | — | — | |
| SCHEMBL11009268 | 0.78 | ALDH1A1 (0.56) | — | |
| SCHEMBL11009265 | 0.78 | ALDH1A1 (0.56) | — | |
| SCHEMBL10131694 | 0.76 | ALDH1A1 (0.41) | — | |
| SCHEMBL294122 | 0.75 | — | — | |
| SCHEMBL301539 | 0.75 | — | — | |
| SCHEMBL1650009 | 0.75 | ALDH1A1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140038181-A1 | CHEMICALLY SUBSTITUTED THERMOSENSITIVE PROBES AND COFACTORS FOR HOT START LIGATION | TRILINK BIOTECHNOLOGIES, INC. | 2014-02-06 | — | — | US | claimed |
| US-8361753-B2 | Phosphotriester-modified oligonucleotide primers for nucleic acid amplification | TRILINK BIOTECHNOLOGIES, INC. (US) | 2013-01-29 | — | — | US | claimed |
| WO-2012094343-A1 | CHEMICALLY SUBSTITUTED THERMOSENSITIVE PROBES AND COFACTORS FOR HOT START LIGATION | TRILINK BIOTECHNOLOGIES (US) | 2012-07-12 | — | — | WO | claimed |
| EP-2032714-B1 | CHEMICALLY MODIFIED OLIGONUCLEOTIDE PRIMERS FOR NUCLEIC ACID AMPLIFICATION | TRILINK BIOTECHNOLOGIES (US) | 2011-03-16 | — | — | EP | claimed |
| EP-1630165-B1 | [1,2,4]TRIAZOLO[1,5-a]PYRIMIDIN-2-YLUREA DERIVATIVE AND USE THEREOF | NIPPON KAYAKU KK (JP) | 2010-03-31 | — | — | EP | claimed |
| US-7598244-B2 | [1,2,4]triazolo[1,5,a]pyrimidin-2-ylurea derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2009-10-06 | — | — | US | claimed |
| EP-2032714-A1 | CHEMICALLY MODIFIED OLIGONUCLEOTIDE PRIMERS FOR NUCLEIC ACID AMPLIFICATION | TriLink BioTechnologies (US) | 2009-03-11 | — | — | EP | claimed |
| WO-2007139723-A1 | CHEMICALLYMODIFIED OLIGONUCLEOTIDE PRIMERS FOR NUCLEIC ACID AMPLIFICATION | TRILINK BIOTECHNOLOGIES (US) | 2007-12-06 | — | — | WO | claimed |
| US-20070281308-A1 | CHEMICALLY MODIFIED OLIGONUCLEOTIDE PRIMERS FOR NUCLEIC ACID AMPLIFICATION | TRILINK BIOTECHNOLOGIES, LLC | 2007-12-06 | — | — | US | claimed |
| US-20070010515-A1 | [1,2,4] Triazolo [1,5, a] pyrimidin-2-ylurea derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2007-01-11 | — | — | US | claimed |
| CN-1809570-A | [1,2,4] triazolo [1, 5-a ] pyrimidin-2-ylurea derivatives and uses thereof | NIPPON KAYAKU KK (JP) | 2006-07-26 | — | — | CN | claimed |
| EP-1630165-A1 | [1,2,4 ]TRIAZOLO [1,5-A]PYRIMIDIN-2-YLUREA DERIVATIVE AND USE THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2006-03-01 | — | — | EP | claimed |
| EP-3842550-A1 | METHOD FOR ANALYZING FUNCTIONAL SUBUNIT PAIR GENE OF T CELL RECEPTOR AND B CELL RECEPTOR | Repertoire Genesis Incorporation (JP) | 2021-06-30 | — | — | EP | disclosed |
| CN-111018811-A | Method for preparing α -chloro- α -acetyl-gamma-butyrolactone | 江西天新药业股份有限公司 | 2020-04-17 | — | — | CN | disclosed |
| WO-2020040302-A1 | METHOD FOR ANALYZING FUNCTIONAL SUBUNIT PAIR GENE OF T CELL RECEPTOR AND B CELL RECEPTOR | Ｒｅｐｅｒｔｏｉｒｅ Ｇｅｎｅｓｉｓ株式会社 | 2020-02-27 | — | — | WO | disclosed |
| EP-3486321-A1 | T-CELL RECEPTOR AND B-CELL RECEPTOR REPERTOIRE ANALYSIS SYSTEM USING ONE-STEP REVERSE TRANSCRIPTION TEMPLATE-SWITCHING PCR | Riken (JP) | 2019-05-22 | — | — | EP | disclosed |
| US-20070010515-A1 | [1,2,4] Triazolo [1,5, a] pyrimidin-2-ylurea derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2007-01-11 | — | — | US | disclosed |
| CN-1809570-A | [1,2,4] triazolo [1, 5-a ] pyrimidin-2-ylurea derivatives and uses thereof | NIPPON KAYAKU KK (JP) | 2006-07-26 | — | — | CN | disclosed |
| EP-1630165-A1 | [1,2,4 ]TRIAZOLO [1,5-A]PYRIMIDIN-2-YLUREA DERIVATIVE AND USE THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2006-03-01 | — | — | EP | disclosed |
| EP-0219257-A2 | Esters of dihydrolysergic acid | ELI LILLY AND COMPANY (US) | 1987-04-22 | — | — | EP | disclosed |