Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1412937 | 0.84 | P2RX7 (0.56) | P2RX7SPR | |
| SCHEMBL1412881 | 0.83 | P2RX7 (0.73) | P2RX7SPR | |
| SCHEMBL1412959 | 0.79 | P2RX7 (0.58) | P2RX7SPR | |
| SCHEMBL1413037 | 0.75 | P2RX7 (0.57) | P2RX7SPR | |
| SCHEMBL1412923 | 0.74 | P2RX7 (0.76) | P2RX7SPR | |
| SCHEMBL1415261 | 0.73 | P2RX7 (0.74) | P2RX7SPR | |
| SCHEMBL5837470 | 0.73 | P2RX7 (0.59) | P2RX7SPR | |
| SCHEMBL5838233 | 0.72 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL1412983 | 0.72 | P2RX7 (0.48) | P2RX7 | |
| SCHEMBL1413075 | 0.71 | P2RX7 (0.67) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448535-B1 | BENZAMIDE AND HETEROARYLAMIDE AS P2X7 RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2011-03-16 | — | — | EP | disclosed |