Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 14/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14130510 | 1.00 | AVPR2 (0.38) | AVPR2HCRTR1HCRTR2PDK2AVPR1A | |
| SCHEMBL14130046 | 0.93 | HCRTR1 (0.39) | AVPR2HCRTR1HCRTR2AVPR1AALDH1A1 | |
| SCHEMBL14130218 | 0.93 | HCRTR1 (0.39) | AVPR2HCRTR1HCRTR2AVPR1AALDH1A1 | |
| SCHEMBL14130104 | 0.92 | HCRTR1 (0.38) | AVPR2HCRTR1HCRTR2PDK2AVPR1A | |
| SCHEMBL14130309 | 0.92 | HCRTR1 (0.38) | AVPR2HCRTR1HCRTR2PDK2AVPR1A | |
| SCHEMBL5059003 | 0.89 | HCRTR1 (0.38) | AVPR2HCRTR1HCRTR2AVPR1A | |
| SCHEMBL14130330 | 0.89 | HCRTR1 (0.38) | AVPR2HCRTR1HCRTR2AVPR1A | |
| SCHEMBL14130493 | 0.88 | HCRTR1 (0.39) | AVPR2HCRTR1HCRTR2PDK2AVPR1A | |
| SCHEMBL5063182 | 0.88 | HCRTR1 (0.39) | AVPR2HCRTR1HCRTR2PDK2AVPR1A | |
| SCHEMBL14130502 | 0.84 | HCRTR1 (0.40) | AVPR2HCRTR1HCRTR2PDK2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161294-A1 | Urea derivative, medicinal composition containing the same, and medicinal use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-07-03 | — | — | US | disclosed |
| US-20080161294-A1 | Urea derivative, medicinal composition containing the same, and medicinal use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161294-A1 | Urea derivative, medicinal composition containing the same, and medicinal use of these | AVPR2, UTS2R, GPR119 | AVPR2 1/4885HCRTR1 119/4885HCRTR2 109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.