Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 15/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14130502 | 0.92 | HCRTR1 (0.40) | HCRTR1HCRTR2AVPR2AVPR1A | |
| SCHEMBL14130181 | 0.91 | HCRTR1 (0.37) | HCRTR1HCRTR2AVPR2AVPR1ATHRB | |
| SCHEMBL14130278 | 0.90 | HCRTR1 (0.39) | HCRTR1HCRTR2AVPR2AVPR1A | |
| SCHEMBL14130324 | 0.89 | HCRTR1 (0.39) | HCRTR1HCRTR2AVPR2AVPR1A | |
| SCHEMBL14130331 | 0.89 | HCRTR1 (0.39) | HCRTR1HCRTR2AVPR2AVPR1A | |
| SCHEMBL14130570 | 0.89 | HCRTR1 (0.40) | HCRTR1HCRTR2AVPR2AVPR1A | |
| SCHEMBL14130569 | 0.89 | HCRTR1 (0.40) | HCRTR1HCRTR2AVPR2AVPR1A | |
| SCHEMBL14130166 | 0.89 | AVPR2 (0.37) | HCRTR1HCRTR2AVPR2AVPR1AOXTR | |
| SCHEMBL14130547 | 0.88 | HCRTR1 (0.40) | HCRTR1HCRTR2AVPR2AVPR1AOXTR | |
| SCHEMBL14130545 | 0.88 | HCRTR1 (0.40) | HCRTR1HCRTR2AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161294-A1 | Urea derivative, medicinal composition containing the same, and medicinal use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-07-03 | — | — | US | disclosed |
| US-20080161294-A1 | Urea derivative, medicinal composition containing the same, and medicinal use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161294-A1 | Urea derivative, medicinal composition containing the same, and medicinal use of these | AVPR2, UTS2R, GPR119 | HCRTR1 119/4885HCRTR2 109/4885AVPR2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.