Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 20/20 | 0.52 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.50 |
| ▸ | OXTR | P30559 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14130377 | 0.89 | AVPR2 (0.66) | AVPR2AVPR1AOXTRCYP3A4CYP2C19 | |
| SCHEMBL5058917 | 0.85 | AVPR2 (0.64) | AVPR2AVPR1AOXTR | |
| SCHEMBL14130144 | 0.85 | AVPR2 (0.64) | AVPR2AVPR1AOXTR | |
| SCHEMBL14130385 | 0.82 | AVPR2 (0.45) | AVPR2AVPR1AOXTR | |
| SCHEMBL5066826 | 0.81 | AVPR2 (0.64) | AVPR2AVPR1A | |
| SCHEMBL14130376 | 0.80 | AVPR2 (0.48) | AVPR2AVPR1AOXTR | |
| SCHEMBL14130379 | 0.79 | AVPR2 (0.61) | AVPR2AVPR1AOXTR | |
| SCHEMBL14130002 | 0.78 | AVPR2 (0.54) | AVPR2AVPR1AOXTRCYP3A4CYP2C19 | |
| SCHEMBL14130260 | 0.78 | AVPR2 (0.48) | AVPR2AVPR1AOXTRCYP3A4CYP2C19 | |
| SCHEMBL14130044 | 0.78 | AVPR2 (0.53) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161294-A1 | Urea derivative, medicinal composition containing the same, and medicinal use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-07-03 | — | — | US | disclosed |
| US-20080161294-A1 | Urea derivative, medicinal composition containing the same, and medicinal use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161294-A1 | Urea derivative, medicinal composition containing the same, and medicinal use of these | AVPR2, UTS2R, GPR119 | AVPR2 1/4885AVPR1A 4/4885OXTR 84/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.