⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14533325 | 0.67 | — | — | |
| SCHEMBL12693418 | 0.67 | — | — | |
| SCHEMBL14000797 | 0.67 | — | — | |
| SCHEMBL18105985 | 0.65 | — | — | |
| SCHEMBL6130806 | 0.61 | — | — | |
| SCHEMBL19129513 | 0.61 | FUCA1 (0.38) | — | |
| SCHEMBL12629749 | 0.60 | — | — | |
| SCHEMBL2210400 | 0.57 | MAOA (0.42) | — | |
| SCHEMBL11370176 | 0.53 | — | — | |
| SCHEMBL18029756 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160200749-A1 | BIOLOGICALLY ACTIVE COMPOUNDS SPECIFICALLY DELIVERED INTO MITOCHONDRIA | MITOTECH SA (LU) | 2016-07-14 | — | — | US | disclosed |
| US-20160200749-A1 | BIOLOGICALLY ACTIVE COMPOUNDS SPECIFICALLY DELIVERED INTO MITOCHONDRIA | MITOTECH SA (LU) | 2016-07-14 | — | — | US | disclosed |
| US-9328130-B2 | Method of treating organism by biologically active compounds specifically delivered into mitochondria, pharmaceutical composition required for the use of the method and a compound applicable for this purpose | MITOTECH S.A. (LU) | 2016-05-03 | — | — | US | disclosed |
| US-9328130-B2 | Method of treating organism by biologically active compounds specifically delivered into mitochondria, pharmaceutical composition required for the use of the method and a compound applicable for this purpose | MITOTECH S.A. (LU) | 2016-05-03 | — | — | US | disclosed |
| US-20080176929-A1 | driven by proton electro-chemical potential; reduction of concentration of free radicals and reactive oxygen species in living cell; antiproliferative, antiinflammatory agent, antioxidant, disinfectant; wound healing, grafting; composition of antioxidant, linker, and charged lipophilic compound/peptide | MITOTECHNOLOGY LLC. (RU) | 2008-07-24 | — | — | US | disclosed |
| US-20080176929-A1 | driven by proton electro-chemical potential; reduction of concentration of free radicals and reactive oxygen species in living cell; antiproliferative, antiinflammatory agent, antioxidant, disinfectant; wound healing, grafting; composition of antioxidant, linker, and charged lipophilic compound/peptide | MITOTECHNOLOGY LLC. (RU) | 2008-07-24 | — | — | US | disclosed |
| WO-2007046729-A1 | METHOD OF ACTING UPON ORGANISM BY TARGETED DELIVERY OF BIOLOGICALY ACTIVE SUBSTANCES INTO M ITOCHONDRIA, PHARMACEUTICAL COMPOSITION FOR CARRYING OUT SAID METHOD, AND COMPOUND USED FOR THE PURPOSE | LIMITED LIABILITY COMPANY 'MITOTECHNOLOGY' (RU) | 2007-04-26 | — | — | WO | disclosed |