Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829825 | 0.85 | TDP1 (0.49) | TDP1MEN1KMT2ACA1CA2 | |
| SCHEMBL11448557 | 0.85 | MEN1 (0.44) | HMGCRHDAC1MEN1KMT2ACA1 | |
| SCHEMBL2958029 | 0.83 | TDP1 (0.40) | TDP1HDAC1MEN1KMT2ACA1 | |
| SCHEMBL29034893 | 0.81 | HMGCR (0.43) | HMGCRTDP1HDAC1EPHX2NR1H4 | |
| SCHEMBL14809201 | 0.81 | MEN1 (0.40) | HMGCRTDP1HDAC1MEN1KMT2A | |
| SCHEMBL9407115 | 0.79 | TDP1 (0.45) | TDP1HDAC1MEN1KMT2ACA1 | |
| SCHEMBL12229746 | 0.79 | NPSR1 (0.45) | HMGCRMEN1KMT2ACA1CA2 | |
| SCHEMBL16243953 | 0.79 | CNR2 (0.46) | TDP1HDAC1MEN1KMT2AEPHX2 | |
| SCHEMBL20782044 | 0.78 | CCNT1 (0.41) | TDP1HDAC1MEN1KMT2ACA1 | |
| SCHEMBL107781 | 0.78 | HPGD (0.48) | TDP1MEN1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100453620-C | Flame retardant phosphonate additives for thermoplastic materials | RHODIA (US) | 2009-01-21 | — | — | CN | disclosed |
| US-7402674-B2 | 7-Phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments | SANOFI-AVENTIS DEUTSCHLAND GMBH, (DE) | 2008-07-22 | — | — | US | disclosed |
| US-7402674-B2 | 7-Phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments | SANOFI-AVENTIS DEUTSCHLAND GMBH, (DE) | 2008-07-22 | — | — | US | disclosed |
| CN-100384937-C | Polylactic acid resin composition | NISSAN CHEMICAL IND LTD (JP) | 2008-04-30 | — | — | CN | disclosed |
| CN-1938378-A | Polylactic acid resin composition | NISSAN CHEMICAL IND LTD (JP) | 2007-03-28 | — | — | CN | disclosed |
| CN-1833015-A | Flame retardant phosphonate additives for thermoplastics | RHODIA (US) | 2006-09-13 | — | — | CN | disclosed |