Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14130804 | 0.81 | HMGCR (0.41) | HMGCRHDAC1EPHX2NR1H4SMN1; SMN2 | |
| SCHEMBL13175075 | 0.80 | HMGCR (0.42) | HMGCRHDAC1NR1H4ALDH1A1MAPT | |
| SCHEMBL12229787 | 0.80 | HMGCR (0.42) | HMGCRHDAC1NR1H4ALDH1A1MAPT | |
| SCHEMBL16868509 | 0.79 | LMNA (0.54) | HDAC1ALDH1A1LMNAMAPT | |
| SCHEMBL6858817 | 0.79 | ESR1 (0.44) | HDAC1ALDH1A1LMNAMAPT | |
| SCHEMBL17223280 | 0.79 | HMGCR (0.43) | HMGCRHDAC1EPHX2NR1H4ALDH1A1 | |
| SCHEMBL12229756 | 0.78 | ALDH1A1 (0.49) | HDAC1ALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL914714 | 0.78 | NPC1 (0.48) | HDAC1ALDH1A1SMN1; SMN2MAPTRECQL | |
| SCHEMBL16868487 | 0.78 | GAA (0.49) | HDAC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL28011653 | 0.78 | ALDH1A1 (0.41) | HDAC1DGAT1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425794-A | Aryl phosphonate compound and preparation method thereof | 烟台大学 | 2023-07-14 | — | — | CN | disclosed |