Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.69 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | C1S | P09871 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3974775 | 0.95 | F10 (0.64) | F10PRSS1NPC1PKMEPHX2 | |
| SCHEMBL14132041 | 0.89 | F10 (0.70) | F10PRSS1NPC1PKMEPHX2 | |
| SCHEMBL14132161 | 0.87 | F10 (0.67) | F10PRSS1NPC1PKMEPHX2 | |
| SCHEMBL14132335 | 0.87 | F10 (0.67) | F10PRSS1NPC1PKMEPHX2 | |
| SCHEMBL13901217 | 0.86 | F10 (0.67) | F10PRSS1NPC1PKMEPHX2 | |
| Trifluoroacetic Acid SCHEMBL3902693 | 0.86 | F10 (0.64) | F10PRSS1NPC1PKMEPHX2 | |
| SCHEMBL3964336 | 0.85 | NPC1 (0.54) | F10NPC1PKMEPHX2RAB9A | |
| SCHEMBL14132165 | 0.85 | F10 (0.65) | F10PKMSMN1; SMN2KMT2A | |
| Trifluoroacetic Acid SCHEMBL3968850 | 0.84 | F10 (0.61) | F10PRSS1NPC1PKMEPHX2 | |
| Trifluoroacetic Acid SCHEMBL3910396 | 0.83 | F10 (0.61) | F10PRSS1NPC1PKMEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |