Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | C1S | P09871 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3902693 | 0.97 | F10 (0.64) | F10ALDH1A1PRSS1F2PLG | |
| SCHEMBL13901217 | 0.95 | F10 (0.67) | F10ALDH1A1PRSS1F2PLG | |
| SCHEMBL14132041 | 0.92 | F10 (0.70) | F10ALDH1A1PRSS1NPC1PKM | |
| Trifluoroacetic Acid SCHEMBL3974775 | 0.89 | F10 (0.64) | F10PRSS1F2PLGPRSS2 | |
| Trifluoroacetic Acid SCHEMBL3968850 | 0.88 | F10 (0.61) | F10PRSS1F2PLGPRSS2 | |
| Trifluoroacetic Acid SCHEMBL3898005 | 0.86 | F10 (0.58) | F10ALDH1A1PRSS1F2PLG | |
| Trifluoroacetic Acid SCHEMBL3968459 | 0.83 | F10 (0.62) | F10PRSS1PRSS2PRSS3 | |
| SCHEMBL14131982 | 0.83 | F10 (0.69) | F10PRSS1F2PLGPRSS2 | |
| Trifluoroacetic Acid SCHEMBL3973028 | 0.82 | F10 (0.90) | F10F2 | |
| Trifluoroacetic Acid SCHEMBL3970578 | 0.82 | F10 (0.61) | F10ALDH1A1PRSS1F2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |