Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.73 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.62 |
| ▸ | F2 | P00734 | 5/20 | 0.58 |
| ▸ | PLG | P00747 | 2/20 | 0.58 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.58 |
| ▸ | C1S | P09871 | 1/20 | 0.58 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.58 |
| ▸ | PROC | P04070 | 1/20 | 0.53 |
| ▸ | KLK1 | P06870 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3901415 | 0.91 | F10 (0.68) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL14132304 | 0.84 | F10 (1.00) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL14132044 | 0.81 | F10 (0.93) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL16450813 | 0.80 | PRSS1 (0.73) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL14367459 | 0.80 | PRSS1 (0.68) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL14132036 | 0.80 | F10 (0.88) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL14132141 | 0.80 | F10 (0.90) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL14132005 | 0.79 | F10 (0.65) | F10PRSS1F2PLGPRSS2 | |
| Hydrochloric Acid SCHEMBL5623120 | 0.79 | PRSS1 (0.69) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL14132167 | 0.79 | F10 (0.88) | F10PRSS1F2PLGPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |