Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.54 |
| ▸ | PLG | P00747 | 3/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | C1S | P09871 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | PROC | P04070 | 1/20 | 0.48 |
| ▸ | KLK1 | P06870 | 1/20 | 0.48 |
| ▸ | HRAS | P01112 | 1/20 | 0.47 |
| ▸ | KRAS | P01116 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3907682 | 0.93 | F10 (0.53) | F10F2 | |
| SCHEMBL3898931 | 0.92 | F10 (0.65) | F10PRSS1PLGF2PRSS2 | |
| SCHEMBL14132042 | 0.89 | F10 (0.61) | F10PRSS1PLGF2PRSS2 | |
| SCHEMBL14132207 | 0.85 | F2 (0.58) | F10PRSS1PLGF2PRSS2 | |
| Trifluoroacetic Acid SCHEMBL3899650 | 0.85 | F10 (0.59) | F10PLGF2 | |
| Trifluoroacetic Acid SCHEMBL3910393 | 0.83 | F2 (0.55) | F10F2 | |
| SCHEMBL3910394 | 0.82 | F2 (0.52) | F10PRSS1F2HRASKRAS | |
| SCHEMBL14132052 | 0.82 | F2 (0.57) | F10PRSS1PLGF2PRSS2 | |
| Trifluoroacetic Acid SCHEMBL3899556 | 0.79 | F2 (0.67) | F10PRSS1PLGF2PRSS2 | |
| SCHEMBL13918681 | 0.79 | KMT2A (0.58) | HRASKRASMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |