Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 12/20 | 0.52 |
| ▸ | TMPRSS6 | Q8IU80 | 5/20 | 0.51 |
| ▸ | F10 | P00742 | 3/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.49 |
| ▸ | HRAS | P01112 | 1/20 | 0.47 |
| ▸ | KRAS | P01116 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3899650 | 0.87 | F10 (0.59) | F2TMPRSS6F10 | |
| SCHEMBL3898931 | 0.85 | F10 (0.65) | F2F10PRSS1HRASKRAS | |
| Trifluoroacetic Acid SCHEMBL3910393 | 0.85 | F2 (0.55) | F2TMPRSS6F10 | |
| SCHEMBL14132042 | 0.84 | F10 (0.61) | F2F10PRSS1HRASKRAS | |
| Trifluoroacetic Acid SCHEMBL3907682 | 0.84 | F10 (0.53) | F2TMPRSS6F10 | |
| SCHEMBL14132247 | 0.82 | F10 (0.55) | F2F10PRSS1HRASKRAS | |
| Trifluoroacetic Acid SCHEMBL3899556 | 0.82 | F2 (0.67) | F2TMPRSS6F10PRSS1HRAS | |
| SCHEMBL14132207 | 0.79 | F2 (0.58) | F2TMPRSS6F10PRSS1HRAS | |
| Trifluoroacetic Acid SCHEMBL3898961 | 0.79 | F2 (0.66) | F2TMPRSS6F10PRSS1 | |
| SCHEMBL14132052 | 0.76 | F2 (0.57) | F2TMPRSS6F10PRSS1HRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |