SCHEMBL1413232

SCHEMBL1413232

O=C(O)CCC(=O)CN1C(=O)c2ccccc2C1=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.70
CA9 Q16790 1/20 0.70
KMT2A Q03164 4/20 0.54
MEN1 O00255 3/20 0.54
ALDH1A1 P00352 6/20 0.51
KDM4E B2RXH2 3/20 0.51
MAPT P10636 2/20 0.51
HPGD P15428 2/20 0.51
HSD17B10 Q99714 2/20 0.51
NPSR1 Q6W5P4 2/20 0.51
CYP1A2 P05177 1/20 0.51
AKR1B1 P15121 1/20 0.51
ALOX15 P16050 1/20 0.51
RAB9A P51151 1/20 0.51
POLB P06746 2/20 0.49
TP53 P04637 1/20 0.49
GLA P06280 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
ALOX12 P18054 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9016051 0.90 CA12 (0.66) CA12CA9KMT2AMEN1ALDH1A1
SCHEMBL1413250 0.85 KDM4E (0.74) CA12CA9KMT2AMEN1ALDH1A1
SCHEMBL10671594 0.85 CA12 (0.59) CA12CA9KMT2AMEN1ALDH1A1
SCHEMBL8940040 0.85 CA12 (0.73) CA12CA9KMT2AMEN1ALDH1A1
SCHEMBL10671092 0.84 ALDH1A1 (0.59) CA12CA9KMT2AMEN1ALDH1A1
SCHEMBL10666782 0.84 CA12 (0.58) CA12CA9KMT2AMEN1ALDH1A1
SCHEMBL11764230 0.83 CA12 (0.56) CA12CA9KMT2AMEN1ALDH1A1
SCHEMBL522649 0.83 CA12 (1.00) CA12CA9KMT2AMEN1ALDH1A1
SCHEMBL29744481 0.83 CA12 (1.00) CA12CA9KMT2AMEN1ALDH1A1
SCHEMBL29602255 0.82 ALDH1A1 (0.59) CA12CA9KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116539780-A Method for simultaneously detecting aminolevulinic acid hydrochloride intermediate and 5 impurities 湖南先施制药有限公司 2023-08-04 CN claimed
CN-111249801-B Decarburizing and filtering device and method for preparing aminolevulinic acid hydrochloride 上海万巷制药有限公司 2021-10-01 CN claimed
CN-111249801-A Decarburizing and filtering device and method for preparing aminolevulinic acid hydrochloride 上海万巷制药有限公司 2020-06-09 CN claimed
US-8022229-B2 Process for the preparation of alkyl 5-(dicarboximido) levulinate and alkyl 4-oxo-pentenoate ALFA-SYNTHON AB (SE) 2011-09-20 US claimed
EP-1833790-B1 PROCESS FOR THE PREPARATION OF ALKYL 5-(DICARBOXIMIDO)LEVULINATE AND ALKYL 4-OXO-PENTENOATE ALFA SYNTHON AB (SE) 2011-03-16 EP claimed
US-20080027233-A1 Process for the Preparation of Alkyl 5-(Dicarboximido) Levulinate and Alkyl 4-Oxopentenoate ESQUIRE AB (SE) 2008-01-31 US claimed
EP-1833790-A1 PROCESS FOR THE PREPARATION OF ALKYL 5-(DICARBOXIMIDO)LEVULINATE AND ALKYL 4-OXO-PENTENOATE Biosynth AB (SE) 2007-09-19 EP claimed
WO-2006048236-A1 PROCESS FOR THE PREPARATION OF ALKYL 5- (DICARBOXIMIDO) LEVULINATE AND ALKYL 4-OXO-PENTENOATE BIOSYNTH AB (SE) 2006-05-11 WO claimed
JP-7238063-A None JP disclosed
CN-116539780-A Method for simultaneously detecting aminolevulinic acid hydrochloride intermediate and 5 impurities 湖南先施制药有限公司 2023-08-04 CN disclosed
CN-111249801-B Decarburizing and filtering device and method for preparing aminolevulinic acid hydrochloride 上海万巷制药有限公司 2021-10-01 CN disclosed
CN-111249801-B Decarburizing and filtering device and method for preparing aminolevulinic acid hydrochloride 上海万巷制药有限公司 2021-10-01 CN disclosed
CN-111592484-A Preparation method of 5-aminolevulinic acid hydrochloride intermediate 上海奈及生物医药科技有限公司 2020-08-28 CN disclosed
CN-111249801-A Decarburizing and filtering device and method for preparing aminolevulinic acid hydrochloride 上海万巷制药有限公司 2020-06-09 CN disclosed
JP-H07238063-A METHOD FOR RECOVERING AND PURIFYING 5-AMINOLEVULINIC ACID COSMO SOGO KENKYUSHO:KK 1995-09-12 JP disclosed
EP-0483714-B1 A method of preparing an acid additional salt of delta-aminolevulinic acid JAPAN TOBACCO INC (JP) 1995-05-03 EP disclosed
US-5380935-A Process for preparing 5-aminolevulinic acid COSMO RESEARCH INSTITUTE (JP) 1995-01-10 US disclosed
EP-0607952-A1 Process for preparing 5-aminolevulinic acid COSMO RESEARCH INSTITUTE (JP) 1994-07-27 EP disclosed
US-5284973-A Method of preparing an acid additional salt of delta-aminolevulinic acid JAPAN TOBACCO INC. (JP) 1994-02-08 US disclosed
EP-0483714-A1 A method of preparing an acid additional salt of delta-aminolevulinic acid Japan Tobacco Inc. (JP) 1992-05-06 EP disclosed