SCHEMBL14132971

SCHEMBL14132971

CCC(=O)NC[C@@H](NC(=O)c1ccc2nc(NC(=O)c3ccccc3-c3ccc(CF)cc3)ccc2c1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ MTTP P55157 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5007646 0.90 MTTP (0.64) MTTP
SCHEMBL14132458 0.82 MTTP (0.68) MTTP
SCHEMBL14215456 0.81 MTTP (0.65) MTTP
SCHEMBL5011810 0.79 MTTP (0.64) MTTP
SCHEMBL13993526 0.79 MTTP (0.64) MTTP
SCHEMBL5668283 0.77 MTTP (0.66) MTTP
SCHEMBL4981759 0.76 MTTP (0.64) MTTP
SCHEMBL13993527 0.76 MTTP (0.72) MTTP
SCHEMBL4991708 0.74 MTTP (0.65) MTTP
SCHEMBL13993525 0.74 MTTP (0.62) MTTP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7393958-B2 Triamide-substituted heterobicyclic compounds PFIZER, INC. (US) 2008-07-01 — — US disclosed
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