SCHEMBL14132458

SCHEMBL14132458

CCCCCNC(=O)[C@@H](NC(=O)c1ccc2nc(NC(=O)c3ccccc3-c3ccc(CF)cc3)ccc2c1)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ MTTP P55157 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14186885 0.91 MTTP (0.70) MTTP
SCHEMBL1600315 0.91 MTTP (0.70) MTTP
SCHEMBL14132971 0.82 MTTP (0.59) MTTP
SCHEMBL14215456 0.80 MTTP (0.65) MTTP
SCHEMBL5669914 0.77 KDM4E (0.48) MTTP
SCHEMBL13993519 0.77 KDM4E (0.48) MTTP
SCHEMBL6890386 0.76 MTTP (0.65) MTTP
SCHEMBL6255880 0.75 MTTP (0.91) MTTP
SCHEMBL4991708 0.75 MTTP (0.65) MTTP
SCHEMBL4986832 0.74 MTTP (0.70) MTTP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7393958-B2 Triamide-substituted heterobicyclic compounds PFIZER, INC. (US) 2008-07-01 — — US disclosed
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