Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 17/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11939511 | 0.89 | HIF1A (0.56) | HIF1AHSP90AA1 | |
| SCHEMBL16867638 | 0.72 | COXFA4 (0.52) | HIF1AHSP90AA1 | |
| SCHEMBL16694297 | 0.72 | COXFA4 (0.52) | HIF1AHSP90AA1 | |
| SCHEMBL12343777 | 0.72 | PTGDR2 (0.38) | HIF1A | |
| SCHEMBL18244727 | 0.71 | HIF1A (1.00) | HIF1AHSP90AA1 | |
| SCHEMBL14134344 | 0.70 | HIF1A (0.51) | HIF1AHSP90AA1 | |
| SCHEMBL21752804 | 0.70 | HIF1A (0.70) | HIF1AHSP90AA1 | |
| SCHEMBL21765950 | 0.70 | HIF1A (0.67) | HIF1AHSP90AA1 | |
| SCHEMBL30860405 | 0.70 | HIF1A (0.70) | HIF1AHSP90AA1 | |
| SCHEMBL16865490 | 0.70 | COXFA4 (0.49) | HIF1AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120302565-A1 | KINASE INHIBITORS FOR PREVENTING OR TREATING PATHOGEN INFECTION AND METHOD OF USE THEREOF | M.D. ANDERSON CANCER CENTER (US) | 2012-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302565-A1 | KINASE INHIBITORS FOR PREVENTING OR TREATING PATHOGEN INFECTION AND METHOD OF USE THEREOF | MAP3K1, MAP3K2, MAP3K6 | HIF1A 980/4885HSP90AA1 625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.