Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14134073 | 0.90 | PHLPP2 (0.39) | PHLPP2THRBENPP2CYP1A2CYP2C9 | |
| SCHEMBL15835812 | 0.88 | PHLPP2 (0.40) | PHLPP2THRBENPP2CYP1A2CYP2C9 | |
| SCHEMBL14134318 | 0.87 | THRB (0.39) | PHLPP2THRBENPP2CYP1A2MEN1 | |
| SCHEMBL14159117 | 0.82 | PHLPP2 (0.52) | PHLPP2THRBENPP2CYP1A2CYP2C9 | |
| SCHEMBL14159105 | 0.82 | PHLPP2 (0.53) | PHLPP2THRBENPP2CYP1A2CYP2C9 | |
| SCHEMBL13387236 | 0.79 | PHLPP2 (0.42) | PHLPP2THRBENPP2CYP1A2CYP2C9 | |
| SCHEMBL24019203 | 0.78 | THRB (0.45) | PHLPP2THRBENPP2CYP1A2CYP2C9 | |
| SCHEMBL14159116 | 0.77 | PHLPP2 (0.43) | PHLPP2THRBENPP2CYP1A2CYP2C9 | |
| SCHEMBL14159099 | 0.77 | THRB (0.43) | PHLPP2THRBENPP2CYP1A2CYP2C9 | |
| SCHEMBL24019208 | 0.76 | PHLPP2 (0.42) | PHLPP2THRBENPP2CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8911509-B2 | Mixtures of fibre-reactive dyes and their use in a method for di- or trichromatic dyeing or printing | HUNTSMAN INTERNATIONAL LLC (US) | 2014-12-16 | — | — | US | disclosed |
| US-20120302486-A1 | Mixtures of Fibre-Reactive Dyes and Their Use in a Method for Di- or Trichromatic Dyeing or Printing | HUNTSMAN INTERNATIONAL LLC (US) | 2012-11-29 | — | — | US | disclosed |