Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | GPBAR1 | Q8TDU6 | 13/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13301977 | 0.87 | GPBAR1 (0.65) | GPBAR1PRKCDNR1H4LMNANT5E | |
| SCHEMBL14134447 | 0.87 | GPBAR1 (0.65) | GPBAR1PRKCDNR1H4LMNANT5E | |
| SCHEMBL17794078 | 0.86 | GPBAR1 (0.52) | SLC10A1PTPN1GPBAR1PRKCDNR1H4 | |
| SCHEMBL13908800 | 0.86 | GPBAR1 (0.52) | SLC10A1PTPN1GPBAR1PRKCDNR1H4 | |
| SCHEMBL10061314 | 0.86 | GPBAR1 (0.52) | SLC10A1PTPN1GPBAR1PRKCDNR1H4 | |
| SCHEMBL13908732 | 0.86 | GPBAR1 (0.52) | SLC10A1PTPN1GPBAR1PRKCDNR1H4 | |
| SCHEMBL27953975 | 0.85 | PTPN1 (0.66) | SLC10A1PTPN1GPBAR1LMNANT5E | |
| SCHEMBL14134450 | 0.83 | PTPN1 (0.61) | PTPN1GPBAR1LMNANT5ESMN1; SMN2 | |
| SCHEMBL13164839 | 0.83 | PTPN1 (0.61) | PTPN1GPBAR1LMNANT5ESMN1; SMN2 | |
| SCHEMBL13301934 | 0.81 | SLC10A1 (0.55) | SLC10A1PTPN1GPBAR1PRKCDNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120302530-A1 | 23-HYDROXY-BETULINIC ACID DERIVATIVES, PREPARATION METHODS AND USES THEREOF | SUZHOU MAIDIXIAN PHARMACEUTICAL INC. (CN) | 2012-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302530-A1 | 23-HYDROXY-BETULINIC ACID DERIVATIVES, PREPARATION METHODS AND USES THEREOF | IL23R, BET1, IL17A | SLC10A1 1744/4885PTPN1 4057/4885GPBAR1 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.