Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.61 |
| ▸ | TOP2A | P11388 | 2/20 | 0.61 |
| ▸ | CES2 | O00748 | 2/20 | 0.61 |
| ▸ | CES1 | P23141 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.59 |
| ▸ | NT5E | P21589 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PTGES | O14684 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | F3 | P13726 | 1/20 | 0.52 |
| ▸ | PREP | P48147 | 2/20 | 0.49 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.49 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13164839 | 1.00 | PTPN1 (0.61) | PTPN1TOP2ACES2CES1LMNA | |
| SCHEMBL13293195 | 0.89 | LMNA (0.67) | PTPN1TOP2ACES2CES1LMNA | |
| SCHEMBL13164844 | 0.88 | PTGES (0.58) | PTPN1TOP2ACES2CES1LMNA | |
| Lupenone SCHEMBL13851777 | 0.88 | GPBAR1 (0.75) | PTPN1TOP2ACES2CES1LMNA | |
| Lupenone SCHEMBL1224027 | 0.88 | GPBAR1 (0.75) | PTPN1TOP2ACES2CES1LMNA | |
| Lupenone SCHEMBL13908802 | 0.88 | GPBAR1 (0.75) | PTPN1TOP2ACES2CES1LMNA | |
| Lupenone SCHEMBL13692854 | 0.88 | GPBAR1 (0.75) | PTPN1TOP2ACES2CES1LMNA | |
| Lupenone SCHEMBL27218586 | 0.88 | GPBAR1 (0.75) | PTPN1TOP2ACES2CES1LMNA | |
| Lupenone SCHEMBL13908727 | 0.88 | GPBAR1 (0.75) | PTPN1TOP2ACES2CES1LMNA | |
| SCHEMBL15457042 | 0.88 | GPBAR1 (0.57) | PTPN1TOP2ACES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120302530-A1 | 23-HYDROXY-BETULINIC ACID DERIVATIVES, PREPARATION METHODS AND USES THEREOF | SUZHOU MAIDIXIAN PHARMACEUTICAL INC. (CN) | 2012-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302530-A1 | 23-HYDROXY-BETULINIC ACID DERIVATIVES, PREPARATION METHODS AND USES THEREOF | IL23R, BET1, IL17A | PTPN1 4057/4885TOP2A 786/4885CES2 2829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.