SCHEMBL1413467

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5411264	0.90	HTR6 (0.56)	HTR6CXCR4LMNAMEN1MAPT
	SCHEMBL1413569	0.89	HTR6 (0.55)	HTR6CXCR4LMNAMEN1MAPT
	SCHEMBL1413818	0.88	HTR6 (0.54)	HTR6CXCR4LMNAMEN1MAPT
	SCHEMBL1413646	0.87	HTR6 (0.53)	HTR6CXCR4LMNAMEN1MAPT
	SCHEMBL1415182	0.85	HTR6 (0.66)	HTR6CXCR4ALDH1A1CYP3A4CYP2D6
	SCHEMBL1413829	0.85	HTR6 (0.52)	HTR6CXCR4LMNAMEN1MAPT
	SCHEMBL1413510	0.85	HTR6 (0.54)	HTR6CXCR4LMNAMEN1MAPT
	SCHEMBL1413725	0.84	HTR6 (0.50)	HTR6CXCR4LMNAMEN1MAPT
	SCHEMBL1413402	0.84	HTR6 (0.57)	HTR6CXCR4ALDH1A1RORC
	SCHEMBL1413321	0.82	HTR6 (0.52)	HTR6CXCR4LMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.