Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 10/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.35 |
| ▸ | CENPE | Q02224 | 1/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4264358 | 0.92 | TACR1 (0.57) | TACR1CCR2GPBAR1 | |
| SCHEMBL10019606 | 0.88 | TACR1 (0.50) | TACR1CCR2GPBAR1 | |
| SCHEMBL5327531 | 0.87 | TACR1 (0.49) | TACR1CCR2GPBAR1 | |
| SCHEMBL5435321 | 0.87 | TACR1 (0.49) | TACR1CCR2GPBAR1 | |
| SCHEMBL493659 | 0.87 | TACR1 (0.49) | TACR1CCR2GPBAR1 | |
| SCHEMBL4259182 | 0.87 | TACR1 (0.49) | TACR1CCR2GPBAR1 | |
| SCHEMBL28185894 | 0.85 | TACR1 (0.48) | TACR1 | |
| SCHEMBL4258143 | 0.82 | TACR1 (0.56) | TACR1CCR2GPBAR1 | |
| SCHEMBL6002625 | 0.79 | TACR1 (0.37) | TACR1GPBAR1 | |
| SCHEMBL3226841 | 0.79 | TACR1 (0.37) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402581-B2 | Azetidine compounds | ALBIREO AB (SE) | 2008-07-22 | — | — | US | disclosed |