Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.57 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 12/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10019606 | 0.94 | TACR1 (0.50) | TACR1CCR2GPBAR1 | |
| SCHEMBL5435321 | 0.93 | TACR1 (0.49) | TACR1CCR2GPBAR1 | |
| SCHEMBL5327531 | 0.93 | TACR1 (0.49) | TACR1CCR2GPBAR1 | |
| SCHEMBL493659 | 0.93 | TACR1 (0.49) | TACR1CCR2GPBAR1 | |
| SCHEMBL4259182 | 0.93 | TACR1 (0.49) | TACR1CCR2GPBAR1 | |
| SCHEMBL14136104 | 0.92 | TACR1 (0.48) | TACR1CCR2GPBAR1 | |
| SCHEMBL28185894 | 0.90 | TACR1 (0.48) | TACR1 | |
| SCHEMBL4258143 | 0.90 | TACR1 (0.56) | TACR1CCR2GPBAR1 | |
| SCHEMBL8099839 | 0.86 | TACR1 (0.54) | TACR1 | |
| SCHEMBL8582371 | 0.86 | TACR1 (0.54) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636221-B1 | 3-Heterocyclyl-Azetidine compounds useful as NK1/NK2 receptors antagonists | ALBIREO AB (SE) | 2009-08-12 | — | — | EP | disclosed |
| EP-1636221-B1 | 3-Heterocyclyl-Azetidine compounds useful as NK1/NK2 receptors antagonists | ALBIREO AB (SE) | 2009-08-12 | — | — | EP | disclosed |
| US-7402581-B2 | Azetidine compounds | ALBIREO AB (SE) | 2008-07-22 | — | — | US | disclosed |
| US-7402581-B2 | Azetidine compounds | ALBIREO AB (SE) | 2008-07-22 | — | — | US | disclosed |
| US-20060172988-A1 | Azetidine compounds | ALBIREO AB (SE) | 2006-08-03 | — | — | US | disclosed |
| EP-1636221-A2 | NEW AZETIDINE COMPOUNDS | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004110344-A2 | NEW AZETIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060172988-A1 | Azetidine compounds | HRH2, HRH4, HRH1 | TACR1 28/4885CCR2 821/4885GPBAR1 1262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.