Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 17/20 | 0.67 |
| ▸ | MMP8 | P22894 | 10/20 | 0.66 |
| ▸ | MMP2 | P08253 | 9/20 | 0.66 |
| ▸ | MMP10 | P09238 | 9/20 | 0.66 |
| ▸ | MMP3 | P08254 | 5/20 | 0.66 |
| ▸ | MMP12 | P39900 | 5/20 | 0.66 |
| ▸ | MMP9 | P14780 | 3/20 | 0.66 |
| ▸ | MMP14 | P50281 | 3/20 | 0.66 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 2/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10289676 | 0.85 | MMP13 (0.65) | MMP13MMP8MMP2MMP10MMP3 | |
| SCHEMBL689658 | 0.80 | MMP13 (1.00) | MMP13MMP8MMP2MMP10MMP3 | |
| SCHEMBL10289432 | 0.80 | MMP13 (0.71) | MMP13MMP8MMP2MMP10MMP3 | |
| SCHEMBL12750104 | 0.80 | MMP13 (0.74) | MMP13MMP8MMP2MMP10MMP3 | |
| SCHEMBL687716 | 0.80 | MMP13 (1.00) | MMP13MMP8MMP2MMP10MMP3 | |
| SCHEMBL12750352 | 0.79 | MMP13 (0.70) | MMP13MMP8MMP2MMP10MMP3 | |
| Hydrochloric Acid SCHEMBL689101 | 0.79 | MMP13 (0.69) | MMP13MMP8MMP2MMP10MMP3 | |
| SCHEMBL4935723 | 0.79 | MMP13 (0.70) | MMP13MMP8MMP2MMP10MMP3 | |
| SCHEMBL689092 | 0.79 | MMP13 (0.80) | MMP13MMP8MMP2MMP10MMP3 | |
| SCHEMBL689901 | 0.78 | MMP13 (0.68) | MMP13MMP8MMP2MMP10MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953148-A1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2008-08-06 | — | — | EP | disclosed |