SCHEMBL14136190

SCHEMBL14136190

C1=Cc2c(c3cc4c(cc3n2-c2cccc(-c3cccc(-n5c6ccccc6c6cc7c(cc65)c5ccccc5n7-c5ccccc5)n3)n2)c2ccccc2n4-c2ccccc2)CC1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19849099 0.93 KDM4E (0.40) KDM4EATML3MBTL1
SCHEMBL13466705 0.92
SCHEMBL13465852 0.92 KDM4E (0.35) KDM4EATML3MBTL1
SCHEMBL13466236 0.92 KDM4E (0.39) KDM4EATML3MBTL1
SCHEMBL18944716 0.91 COMT (0.34)
SCHEMBL18944725 0.83 MKNK1 (0.31)
SCHEMBL10061790 0.83 L3MBTL1 (0.55) KDM4EATML3MBTL1
SCHEMBL10206003 0.83 L3MBTL1 (0.55) KDM4EATML3MBTL1
SCHEMBL20123300 0.82 MKNK1 (0.33) KDM4EATML3MBTL1
SCHEMBL13466681 0.81 KDM4E (0.34) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1956022-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel Chemical Co., Ltd. (JP) 2008-08-13 EP disclosed