Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21232243 | 0.91 | TSHR (0.41) | TSHRKDM4EKMT2A | |
| SCHEMBL20063317 | 0.91 | ALDH1A1 (0.37) | TSHRALDH1A1RAB9AKDM4EMEN1 | |
| SCHEMBL98701 | 0.89 | TSHR (0.40) | TSHRALDH1A1RAB9AKCNA5KDM4E | |
| SCHEMBL3533554 | 0.86 | ALDH1A1 (0.40) | TSHRALDH1A1RAB9AKDM4EMEN1 | |
| SCHEMBL24688602 | 0.86 | TSHR (0.45) | TSHRALDH1A1KDM4EKMT2AACHE | |
| SCHEMBL18427267 | 0.84 | TSHR (0.36) | TSHRALDH1A1RAB9AKCNA5KDM4E | |
| SCHEMBL9640527 | 0.84 | TSHR (0.36) | TSHRKCNA5KDM4EKMT2A | |
| SCHEMBL19774701 | 0.84 | TSHR (0.36) | TSHRALDH1A1RAB9AKCNA5KDM4E | |
| SCHEMBL1010512 | 0.84 | TSHR (0.40) | TSHRALDH1A1RAB9AKCNA5KDM4E | |
| SCHEMBL18376638 | 0.83 | TSHR (0.38) | TSHRKCNA5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012162061-A1 | DELIVERY OF COATED HYDROPHOBIC ACTIVE AGENT PARTICLES | SURMODICS, INC. (US) | 2012-11-29 | — | — | WO | disclosed |