Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.39 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451632 | 0.85 | KDM4E (0.57) | DPP4CYP3A4DPP9DPP7CHRNA10 | |
| SCHEMBL467367 | 0.84 | MCHR1 (0.47) | CYP3A4CHRNA10CHRNA9KDM4ETP53 | |
| Hydrochloric Acid SCHEMBL7339715 | 0.83 | MCHR1 (0.47) | CYP3A4CHRNA10CHRNA9KDM4ETP53 | |
| SCHEMBL14183554 | 0.82 | KCNJ1 (0.50) | LSS | |
| SCHEMBL27629490 | 0.75 | NPY5R (0.46) | DPP4CYP3A4CHRNA10CHRNA9KDM4E | |
| SCHEMBL7225036 | 0.74 | KDM4E (0.53) | CYP3A4CHRNA10CHRNA9KDM4ETP53 | |
| SCHEMBL7338838 | 0.74 | CHIA (0.47) | CYP3A4CHRNA10CHRNA9KDM4ETP53 | |
| SCHEMBL9451684 | 0.73 | KDM4E (0.49) | LSSKDM4ETP53MCHR1RORC | |
| SCHEMBL25087719 | 0.73 | HRH3 (0.68) | DPP4DPP9DPP7NOS3NOS1 | |
| SCHEMBL9147472 | 0.72 | DPP4 (0.47) | DPP4DPP9DPP7NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1950199-A1 | Proline derivatives and use thereof as drugs | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-07-30 | — | — | EP | disclosed |