Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | DPP4 | P27487 | 3/20 | 0.52 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.50 |
| ▸ | HRH1 | P35367 | 4/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | NSD2 | O96028 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.41 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL467367 | 0.88 | MCHR1 (0.47) | KDM4ETP53CYP2D6HRH1CHRM1 | |
| Hydrochloric Acid SCHEMBL7339715 | 0.86 | MCHR1 (0.47) | KDM4ETP53CYP2D6HRH1CHRM1 | |
| SCHEMBL14136358 | 0.85 | DPP4 (0.43) | KDM4ETP53DPP4DPP9DPP7 | |
| SCHEMBL9451716 | 0.84 | LSS (0.55) | TP53CYP2D6HRH1CHRM1KCNH2 | |
| SCHEMBL9451671 | 0.84 | MAPT (0.54) | KDM4ECYP2D6HRH1CHRM1KCNH2 | |
| SCHEMBL14183554 | 0.83 | KCNJ1 (0.50) | KCNH2 | |
| SCHEMBL9451676 | 0.80 | USP2 (0.52) | KDM4ETP53CYP2D6HRH1CHRM1 | |
| SCHEMBL9451538 | 0.80 | MAPT (0.48) | KDM4ETP53CYP2D6HRH1CHRM1 | |
| SCHEMBL9451695 | 0.79 | POLB (0.59) | CYP2D6HRH1CHRM1KCNH2 | |
| SCHEMBL7225036 | 0.77 | KDM4E (0.53) | KDM4ETP53HRH1KDM1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260318-A | Phenylpiperidylamines and drugs containing them | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |