Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14060245 | 0.93 | DGAT1 (0.70) | DGAT1 | |
| SCHEMBL14060073 | 0.93 | DGAT1 (0.80) | DGAT1 | |
| SCHEMBL14060150 | 0.91 | DGAT1 (0.80) | DGAT1 | |
| SCHEMBL14060307 | 0.91 | DGAT1 (0.80) | DGAT1 | |
| SCHEMBL14060147 | 0.91 | DGAT1 (0.80) | DGAT1 | |
| SCHEMBL17200616 | 0.89 | DGAT1 (0.81) | DGAT1 | |
| SCHEMBL14137091 | 0.89 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL14059629 | 0.86 | DGAT1 (0.64) | DGAT1 | |
| SCHEMBL14059665 | 0.85 | DGAT1 (0.70) | DGAT1 | |
| SCHEMBL14060264 | 0.84 | DGAT1 (0.67) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012162127-A1 | NOVEL COMPOUNDS AS DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-11-29 | — | — | WO | disclosed |