Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.34 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | SDCBP | O00560 | 1/20 | 0.32 |
| ▸ | SDC2 | P34741 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14142216 | 0.90 | KMT2A (0.35) | KMT2AFNTAFNTBMAP1LC3BDDB1 | |
| SCHEMBL14294653 | 0.86 | MAP1LC3B (0.39) | KMT2AMAP1LC3BDDB1CRBNALDH1A1 | |
| SCHEMBL14142180 | 0.86 | MAP1LC3B (0.39) | KMT2AMAP1LC3BDDB1CRBNALDH1A1 | |
| SCHEMBL14142266 | 0.85 | KMT2A (0.43) | KMT2ADDB1CRBNELANETSHR | |
| Alanine SCHEMBL14142108 | 0.84 | DDB1 (0.40) | KMT2AMAP1LC3BDDB1CRBNELANE | |
| SCHEMBL2919213 | 0.84 | CYP3A4 (0.39) | KMT2AMAP1LC3BDDB1CRBNALDH1A1 | |
| SCHEMBL2915694 | 0.84 | CYP3A4 (0.39) | KMT2AMAP1LC3BDDB1CRBNALDH1A1 | |
| Bromoacetic Acid SCHEMBL4940372 | 0.84 | DDB1 (0.41) | MAP1LC3BDDB1CRBNALDH1A1CHRM2 | |
| SCHEMBL14142420 | 0.83 | PREP (0.42) | ELANEALDH1A1CYP1A2 | |
| Valine SCHEMBL14142152 | 0.82 | DDB1 (0.37) | KMT2AMAP1LC3BDDB1CRBNELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867649-B1 | PIPERIDYL-2, 6-DIONE DERIVATIVES USED TO INHIBIT CELLS FROM RELEASING TUMOR NECROSIS FACTOR | TIAN JIN HEMAY BIO TECH CO LTD (CN) | 2012-12-12 | — | — | EP | claimed |