Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 4/20 | 0.44 |
| ▸ | F11 | P03951 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830346 | 0.90 | F10 (0.53) | ALDH1A1HPGDF10SMN1; SMN2MAPT | |
| SCHEMBL8467270 | 0.81 | SMN1; SMN2 (0.46) | F10CYP2C9SMN1; SMN2CYP2C19RAB9A | |
| SCHEMBL3830434 | 0.80 | F10 (0.55) | ALDH1A1F10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5829868 | 0.80 | F10 (0.64) | HPGDF10 | |
| SCHEMBL3830301 | 0.80 | F10 (0.63) | ALDH1A1HPGDF10SMN1; SMN2NPC1 | |
| SCHEMBL3835344 | 0.80 | F10 (0.49) | ALDH1A1HPGDF10SMN1; SMN2RAB9A | |
| SCHEMBL3830318 | 0.80 | F10 (0.65) | F10MAPT | |
| SCHEMBL3833960 | 0.78 | F10 (0.48) | ALDH1A1F10SMN1; SMN2RAB9APOLB | |
| SCHEMBL3832358 | 0.77 | F10 (0.51) | ALDH1A1HPGDF10SMN1; SMN2RAB9A | |
| SCHEMBL4101719 | 0.77 | F10 (0.60) | ALDH1A1F10CYP2C9CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1671949-B1 | Substituted Pyridinylamines | WARNER LAMBERT CO (US) | 2008-07-23 | — | — | EP | disclosed |